Article
[Interrelationship between polymorphic markers of methylenetetrahydrofolate reductase gene and development of acute disturbance of brain circulation in families of patients with atrial fibrillation].
Kardiologiia - 1 Jan 2013
Aksiutina N V, Nikulina S Iu, Shul'man V A, Nazarov B V, Dudkina K V, Bezruk G V, Balog A I, Kotlovskiĭ Iu V, Osedko O Ia, Kovaleva O A, Shteĭnerdt S V, Chernova A A
Abstract excerpt
In the present work we for the first time on the clinic-genetic material revealed genetic predictors of development of acute disturbance of brain circulation (ADBC) in families of patients with atrial fibrillation (AF) namely polymorphism of the methylenetetrahydrofolate reductase (MTHFR) gene. Genotype CC was significantly more often found among patients with AF and ADBC compared with controls (58.1 and 35.2%,...
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