Article
Correlation of rapid phenotypic changes and insulin production of differentiated human adipose tissue-derived stem cells.
Annals of plastic surgery - 1 Oct 2009
Scholz Thomas, Satyanarayan Sapna, Dhar Sanjay, Evans Gregory R D
Abstract excerpt
The study investigates adipose tissue-derived stem cells (ADSCs) to differentiate into insulin-secreting cells in vitro. ADSCs were exposed to differentiation medium or control medium. Culture medium was harvested for quantification of insulin and cells were classified into stages of differentiation ranging from normal appearance to islet-like clusters. Morphologic analysis demonstrated marked phenotypic changes...
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