Article
Long polar fimbriae contribute to colonization by Escherichia coli O157:H7 in vivo.
Infection and immunity - 1 Oct 2004
Jordan Dianna M, Cornick Nancy, Torres Alfredo G, Dean-Nystrom Evelyn A, Kaper James B, Moon Harley W
Abstract excerpt
The contribution of long polar fimbriae to intestinal colonization by Escherichia coli O157:H7 was evaluated in sheep, conventional pigs, and gnotobiotic piglets. E. coli O157:H7 strains with lpfA1 and lpfA2 mutated were recovered in significantly lower numbers and caused fewer attachment and effacement lesions than the parent strain.
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