Article
Long polar fimbriae and tissue tropism in Escherichia coli O157:H7.
Microbes and infection - 1 Jun 2006
Fitzhenry Robert, Dahan Sivan, Torres Alfredo G, Chong Yuwen, Heuschkel Robert, Murch Simon H, Thomson Mike, Kaper James B, Frankel Gad, Phillips Alan D
Abstract excerpt
In vitro organ culture has demonstrated the human intestinal tropism of enterohaemorrhagic Escherichia coli O157:H7 for follicle associated epithelium overlying Peyer's patches of the terminal ileum. Long polar (LP) fimbriae are considered to mediate the attachment of Salmonella enterica serovar Typhimurium to Peyer's patch epithelium and, as homologous genes have been identified in O157:H7, we hypothesised that...
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