Article
Host cell tropism underlies species restriction of human and bovine Cryptosporidium parvum genotypes.
Infection and immunity - 1 Oct 2004
Hashim Amna, Clyne Marguerite, Mulcahy Grace, Akiyoshi Donna, Chalmers Rachel, Bourke Billy
Abstract excerpt
It has been recognized recently that human cryptosporidiosis is usually caused by Cryptosporidium parvum genotype I ("human" C. parvum), which is not found in animals. Compared to C. parvum genotype II, little is known of the biology of invasion of the human-restricted C. parvum genotype I. The aims of the present study were (i) to explore and compare with genotype II the pathogenesis of C. parvum genotype I...
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