Article
A directed screen for genes involved in Drosophila blood cell activation.
Proceedings of the National Academy of Sciences of the United States of America - 28 Sept 2004
Zettervall Carl-Johan, Anderl Ines, Williams Michael J, Palmer Ruth, Kurucz Eva, Ando Istvan, Hultmark Dan
Abstract excerpt
An attack by a parasitic wasp activates a vigorous cellular immune response in Drosophila larvae. This response is manifested by an increased number of circulating cells, the hemocytes, and by the appearance of a specialized class of hemocyte, the lamellocytes, which participate in the encapsulation and killing of the parasite. To study the molecular mechanisms of this response, we have overexpressed different...
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