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Article

Familial breast and ovarian cancers.

International journal of clinical oncology - 1 Aug 2004

Arai Masami, Utsunomiya Joji, Miki Yoshio

Abstract excerpt

About 60% of familial breast and ovarian cancers in Japan involve germline mutations of the BRCA1 or BRCA2 ( BRCA1/2) genes. These genes contribute to genetic stability and DNA repair and act as tumor suppressor genes. Mutation analysis of the BRCA1/2 genes has improved our understanding of both...

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Source

Identifiers

PMID: 15375703
DOI: 10.1007/s10147-004-0423-3

Genes

BRCA1
BRCA2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026. Prepared record publication-15375703-2026-09-01.1. Manifest publication-graph-cohort-2026-09-01.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 1 Sept 2026.

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