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[The clinical study of familial breast cancer - now and the problems].

Gan to kagaku ryoho. Cancer & chemotherapy - 1 Apr 2012

Nomizu Tadashi, Matsuzaki Masami, Katagata Naoto, Watanabe Fumiaki, Akama Yoshinori

Abstract excerpt

The clinical features of familial breast cancer are characterized by early onset, high frequency of bilateral breast cancer, and multiple malignancies of other organs. It is strongly suggested that genetic factors contribute to familial breast cancer. The causative genes now identified are BRCA1 and BRCA2. This disease is called hereditary breast ovarian cancer syndrome (HBOC)because breast cancer and ovarian...

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Identifiers

PMID: 22504672

Genes

BRCA1
BRCA2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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