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Article

Gene Expression Profiling of Gliomas Strongly Predicts Survival

15 Sept 2004

Abstract excerpt

In current clinical practice, histology-based grading of diffuse infiltrative gliomas is the best predictor of patient survival time. Yet histology provides little insight into the underlying biology of gliomas and is limited in its ability to identify and guide new molecularly targeted therapies. We have performed large-scale gene expression analysis using the Affymetrix HG U133 oligonucleotide arrays on 85...

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PMID: 15374961
DOI: 10.1158/0008-5472.can-04-0452

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