Article
Timing and reconstruction of the most recent common ancestor of the subtype C clade of human immunodeficiency virus type 1.
Journal of virology - 1 Oct 2004
Travers Simon A A, Clewley Jonathan P, Glynn Judith R, Fine Paul E M, Crampin Amelia C, Sibande Felix, Mulawa Dominic, McInerney James O, McCormack Grace P
Abstract excerpt
Human immunodeficiency virus type 1 (HIV-1) subtype C is responsible for more than 55% of HIV-1 infections worldwide. When this subtype first emerged is unknown. We have analyzed all available gag (p17 and p24) and env (C2-V3) subtype C sequences with known sampling dates, which ranged from 1983 to 2000. The majority of these sequences come from the Karonga District in Malawi and include some of the earliest...
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