Article
Reduced KIAA0471 mRNA expression in Alzheimer's patients: a new candidate gene product linked to the disease?
Human molecular genetics - 1 Nov 2004
de Yebra Lluïsa, Adroer Rosa, de Gregorio-Rocasolano Nuria, Blesa Rafael, Trullas Ramon, Mahy Nicole
Abstract excerpt
Alzheimer's disease (AD) phenotype complexity raises the question whether genetic features remain unknown. Although a few percentage of patients are familial cases linked to mutations in amyloid precursor protein, presenilin 1 or presenilin 2 genes, the remainder are considered mainly sporadic late-onset cases with a complex etiology. However, changes in gene expression or other genetic features of the individual...
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