Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Investigating TBP CAG/CAA trinucleotide repeat expansions in a Taiwanese cohort with ALS.

Amyotrophic lateral sclerosis & frontotemporal degeneration - 1 Aug 2021

Jih Kang-Yang, Lin Kon-Ping, Tsai Pei-Chien, Soong Bing-Wen, Liao Yi-Chu, Lee Yi-Chung

Abstract excerpt

Intermediate-length CAG repeats in ATXN2 have been well recognized as a genetic risk factor for amyotrophic lateral sclerosis (ALS). However, the role of similar trinucleotide repeat expansions in the TATA-box binding protein gene (TBP), another disease-associated gene for inherited ataxia, in ALS remains elusive. To assess the association between TBP trinucleotide repeat expansions and ALS, we investigated the...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Alleles
Share to Amyotrophic Lateral Sclerosis

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Cohort Studies

Share to Risk Factors

Share to TATA-Box Binding Protein

Share to Trinucleotide Repeat Expansion

Source

Identifiers

PMID: 33377399
DOI: 10.1080/21678421.2020.1867182

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Investigating TBP CAG/CAA trinucleotide repeat expansions in a Taiwanese cohort with ALS.PMID 33377399Read ↗

ATXN2 trinucleotide repeat length correlates with risk of ALS.Semantic proximity Read ↗

Reduced-penetrance Huntington's disease-causing alleles with 39 CAG trinucleotide repeats could be a genetic factor of amyotrophic lateral sclerosis.Semantic proximity Read ↗

Intermediate Repeat Expansion in ATXN2 Gene as a Risk Factor in ALS and FTD Spanish PopulationSemantic proximity Read ↗

ATXN2 CAG repeat expansions increase the risk for Chinese patients with amyotrophic lateral sclerosisSemantic proximity Read ↗

Intermediate Repeat Expansion in the ATXN2 Gene as a Risk Factor in the ALS and FTD Spanish PopulationSemantic proximity Read ↗

Intermediate-length polyglutamine in ATXN2 is a possible risk factor among Eastern Chinese patients with amyotrophic lateral sclerosis.Semantic proximity Read ↗

Analysis of polyglutamine-coding repeats in the TATA-binding protein in different neurodegenerative diseases.Semantic proximity Read ↗

A hexanucleotide repeat expansion in C9ORF72 causes familial and sporadic ALS in Taiwan.Semantic proximity Read ↗

Amyotrophic Lateral Sclerosis Risk for Spinocerebellar Ataxia Type 2 ATXN2 CAG Repeat AllelesSemantic proximity Read ↗

Different types of repeat expansion in the TATA-binding protein gene are associated with a new form of inherited ataxia.Semantic proximity Read ↗

Intermediate CAG repeat expansion in the ATXN2 gene is a unique genetic risk factor for ALS--a systematic review and meta-analysis of observational studies.Semantic proximity Read ↗

ATAXIN2 CAG-repeat length in Italian patients with amyotrophic lateral sclerosis: risk factor or variant phenotype? Implication for genetic testing and counseling.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.