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Article

Mitochondria-specific function of the dynamin family protein DLP1 is mediated by its C-terminal domains.

The Journal of biological chemistry - 26 Nov 2004

Pitts Kelly R, McNiven Mark A, Yoon Yisang

Abstract excerpt

The dynamin superfamily of large GTPases has been implicated in a variety of distinct intracellular membrane remodeling events. One of these family members, DLP1/Drp1, is similar to conventional dynamins as it contains an N-terminal GTPase domain followed by a middle region (MID), an unconserved region (UC), and a coiled-coil (CC) domain. DLP1 has been shown to function in membrane-based processes distinct from...

Topics

Dynamins
GTP Phosphohydrolases
Humans
Microtubule-Associated Proteins
Mitochondria
Mitochondrial Proteins
Mutation
Protein Structure, Tertiary
Recombinant Fusion Proteins
Transfection

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 15364948
DOI: 10.1074/jbc.M405531200

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