Article
Analysis of the transforming growth factor-beta 1 gene promoter polymorphisms in early osseointegrated implant failure.
Implant dentistry - 1 Sept 2004
Dos Santos Maria Cristina Leme Godoy, Campos Maria Isabela Guimarães, Souza Ana Paula, Scarel-Caminaga Raquel Mantuaneli, Mazzonetto Renato, Line Sergio Roberto Peres
Abstract excerpt
Transforming growth factor-beta 1 is a multifunctional cytokine involved in extracellular matrix deposition, reduction of inflammation, and promotion of wound healing. Single nucleotide polymorphisms in the promoter region of human transforming growth factor-beta 1 gene, C-509T and G-800A, have been shown to increase the transcriptional activity of this cytokine and have been associated with a variety of...
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