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Article

Early failure of dental implants and TNF-alpha (G-308A) gene polymorphism.

Implant dentistry - 1 Mar 2004

Campos Maria Isabela Guimarães, dos Santos Maria Cristina Leme Godoy, Trevilatto Paula Cristina, Scarel-Caminaga Raquel Mantuaneli, Bezerra Fábio José Barbosa, Line Sergio Roberto Peres

Abstract excerpt

Tumor necrosis factor-alpha (TNF-alpha) is a potent inflammatory mediator with bone resorption activity. Polymorphisms in the promoter region of the human TNF-alpha gene have been shown to affect the levels of this cytokine and have been associated with a variety of diseases. The aim of this study was to investigate the possible relationship between early implant failure and a single nucleotide polymorphism (SNP)...

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Identifiers

PMID: 15017311
DOI: 10.1097/01.id.0000116458.60585.c4

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TNF

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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