Article
Evidence of early ovarian aging in fragile X premutation carriers.
The Journal of clinical endocrinology and metabolism - 1 Sept 2004
Welt C K, Smith P C, Taylor A E
Abstract excerpt
Up to 28% of female fragile X premutation carriers develop premature ovarian failure. To test the hypothesis that fragile X premutation carriers with ovulatory menstrual cycles exhibit hormone changes characteristic of early ovarian aging, 11 regularly cycling fragile X premutation carriers, 24-41 yr old (34.5 +/- 5.7 yr, mean +/- sd), drew daily blood samples across one menstrual cycle. LH, FSH, estradiol,...
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