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Article

Conserved extracellular cysteine residues and cytoplasmic loop-loop interplay are required for functionality of the heptahelical MLO protein.

The Biochemical journal - 1 Jan 2005

Elliott Candace, Müller Judith, Miklis Marco, Bhat Riyaz A, Schulze-Lefert Paul, Panstruga Ralph

Abstract excerpt

We performed a structure-function analysis of the plasma membrane-localized plant-specific barley (Hordeum vulgare) MLO (powdery-mildew-resistance gene o) protein. Invariant cysteine and proline residues, located either in extracellular loops or transmembrane domains that have been conserved in MLO proteins for more than 400 million years, were found to be essential for MLO functionality and/or stability....

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Identifiers

PMID: 15352871
DOI: 10.1042/BJ20040993
PMCID: PMC1134693

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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