Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Potentiation of androgen receptor transcriptional activity by inhibition of histone deacetylation--rescue of transcriptionally compromised mutants.

The Journal of endocrinology - 1 Sept 2004

Korkmaz C G, Frønsdal K, Zhang Y, Lorenzo P I, Saatcioglu F

Abstract excerpt

Androgens are critical in the development and maintenance of the male reproductive system and important in the progression of prostate cancer. The effects of androgens are mediated by the androgen receptor (AR), which is a ligand-modulated transcription factor that belongs to the nuclear receptor superfamily. We and others have previously shown that CREB-binding protein (CBP) can function as a coactivator for AR....

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Acetylation
Share to Blotting, Northern

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Butyrates

Share to Depsipeptides

Share to Histone Deacetylase Inhibitors

Share to Hydroxamic Acids

Share to Peptides, Cyclic

Share to Receptors, Androgen

Source

Identifiers

PMID: 15350180
DOI: 10.1677/joe.0.1820377

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Potentiation of androgen receptor transcriptional activity by inhibition of histone deacetylation--rescue of transcriptionally compromised mutants.PMID 15350180Read ↗

Histone Deacetylases Are Required for Androgen Receptor Function in Hormone-Sensitive and Castrate-Resistant Prostate CancerSemantic proximity Read ↗

Lysine Acetyltransferases and Their Role in AR Signaling and Prostate CancerSemantic proximity Read ↗

Specific properties of a C-terminal truncated androgen receptor detected in hormone refractory prostate cancer.Semantic proximity Read ↗

Defining the molecular action of HDAC inhibitors and synergism with androgen deprivation in ERG‐positive prostate cancerSemantic proximity Read ↗

Androgen receptor acetylation sites differentially regulate gene control.Semantic proximity Read ↗

The chromatin remodeling factor SRCAP modulates expression of prostate specific antigen and cellular proliferation in prostate cancer cellsSemantic proximity Read ↗

The Amino Terminus of the Human AR Is Target for Corepressor Action and Antihormone AgonismSemantic proximity Read ↗

Validation of histone deacetylase 3 as a therapeutic target in castration‐resistant prostate cancerSemantic proximity Read ↗

Transient, ligand-dependent arrest of the androgen receptor in subnuclear foci alters phosphorylation and coactivator interactions.Semantic proximity Read ↗

The Hinge Region Regulates DNA Binding, Nuclear Translocation, and Transactivation of the Androgen ReceptorSemantic proximity Read ↗

Cyclin D1 binds the androgen receptor and regulates hormone-dependent signaling in a p300/CBP-associated factor (P/CAF)-dependent manner.Semantic proximity Read ↗

Androgen receptor interacts with the positive elongation factor P-TEFb and enhances the efficiency of transcriptional elongation.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.