Article
Genotype determines phenotype in experimental Lyme borreliosis.
Annals of neurology - 1 Sept 2004
Pachner Andrew R, Dail Donna, Bai Yunhong, Sondey Marie, Pak Lena, Narayan Kavitha, Cadavid Diego
Abstract excerpt
Borrelia burgdorferi sensu lato, the causative organism of Lyme borreliosis, is a heterogeneous group of spirochetes, consisting of at least three pathogenic species. To test the hypothesis that the genetic heterogeneity is the reason for the clinical differences, we investigated whether the experimental disease induced by European isolates is different from that induced by American isolates. Two American...
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