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Article

Catalase reaction by myoglobin mutants and native catalase: mechanistic investigation by kinetic isotope effect.

The Journal of biological chemistry - 10 Dec 2004

Kato Shigeru, Ueno Takafumi, Fukuzumi Shunichi, Watanabe Yoshihito

Abstract excerpt

The catalase reaction has been studied in detail by using myoglobin (Mb) mutants. Compound I of Mb mutants (Mb-I), a ferryl species (Fe(IV)=O) paired with a porphyrin radical cation, is readily prepared by the reaction with a nearly stoichiometric amount of m-chloroperbenzoic acid. Upon the addition of H2O2 to an Mb-I solution, Mb-I is reduced back to the ferric state without forming any intermediates. This...

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Identifiers

PMID: 15347658
DOI: 10.1074/jbc.M403532200

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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