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Disruption of Plasmodium berghei merozoite surface protein 7 gene modulates parasite growth in vivo

1 Sept 2004

Abstract excerpt

Merozoite invasion of red blood cells is crucial to the development of the parasite that causes malaria. Merozoite surface proteins (MSPs) mediate the first interaction between parasite and erythrocyte. In Plasmodium falciparum, they include a complex of products from at least 3 genes (msp1, msp6, and msp7), one of which, msp7, is part of a gene family containing 3 and 6 adjacent members in Plasmodium yoelii and...

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PMID: 15339842
DOI: 10.1182/blood-2004-06-2106

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