Article
N-Acetyltransferase 2 gene polymorphism in a group of senile dementia patients in Shanghai suburb.
Acta pharmacologica Sinica - 1 Sept 2004
Guo Wei-Chao, Lin Guo-Fang, Zha Yong-Lin, Lou Ke-Jian, Ma Qing-Wen, Shen Jian-Hua
Abstract excerpt
AIM: To investigate the possible association of hereditary polymorphism of N-acetyltransferase 2 (NAT2) gene with the susceptibility towards senile dementia in farmer population of Shanghai suburb. METHODS: NAT2 gene genotyping was performed at 7 major polymorphic loci (G191A, C282T, T341C, C481T, G590A, A803G, and G857A) with a polymerase chain reaction-based restriction fragment length polymorphism based...
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