Article
THTA, a thermotolerance gene of Aspergillus fumigatus.
Fungal genetics and biology : FG & B - 1 Sept 2004
Chang Yun C, Tsai Huei-Fung, Karos Marvin, Kwon-Chung K J
Abstract excerpt
Aspergillus fumigatus grows optimally from 37 to 42 degrees C but can grow at temperatures up to 55 degrees C. To study the genetic basis of thermotolerance and its role in virulence of A. fumigatus, temperature sensitive mutants were isolated. One of the mutants that grew at 42 degrees C but not at 48 degrees C was complemented and the gene, THTA, was identified. Deletion of THTA showed the same temperature...
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