Article
High frequency of selection of K65R and Q151M mutations in HIV-2 infected patients receiving nucleoside reverse transcriptase inhibitors containing regimen.
Journal of medical virology - 1 Oct 2004
Descamps Diane, Damond Florence, Matheron Sophie, Collin Gilles, Campa Pauline, Delarue Severine, Pueyo Sophie, Chêne Genevieve, Brun-Vézinet Francoise
Abstract excerpt
The objective of the study was to determine retrospectively which substitutions in the reverse transcriptase (RT) gene are selected in vivo during nucleoside RT inhibitors (NRTI) containing regimen in HIV-2 infected subjects. Thirty-four HIV-2 patients having received NRTI-containing regimen with available specimens and amplifiable RT gene were studied. Analyses of RT gene were undertaken after a median NRTI...
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