Article
JAM4 enhances hepatocyte growth factor-mediated branching and scattering of Madin-Darby canine kidney cells.
Genes to cells : devoted to molecular & cellular mechanisms - 1 Sept 2004
Mori Hiroki, Hirabayashi Susumu, Shirasawa Madoka, Sugimura Haruhiko, Hata Yutaka
Abstract excerpt
Junctional adhesion molecule (JAM) 4 is a member of immunoglobulin superfamily that interacts with MAGI-1, a membrane-associated guanylate kinase protein at tight junctions in epithelial cells. We prepared Madin-Darby canine kidney II (MDCK) cells expressing JAM4 (MDCK-JAM4) and compared them with wild MDCK cells. The treatment of hepatocyte growth factor (HGF) induced more prominent branching and scattering in...
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