Article
The development of longitudinal variation of Myosin isoforms in the orbital fibers of extraocular muscles of rats.
Investigative ophthalmology & visual science - 1 Sept 2004
Rubinstein Neal A, Porter John D, Hoh Joseph F Y
Abstract excerpt
PURPOSE: To examine the appearance of longitudinal variation of extraocular and embryonic myosin heavy chain (MyHC) isoforms during the development of orbital singly innervated fibers of rat extraocular muscles (EOMs). METHODS: EOMs were dissected from rat pups of various ages and stained with isoform-specific monoclonal antibodies to the embryonic and extraocular MyHC isoforms and to neurofilaments, as well as...
Topics
- Animals
- Animals, Newborn
- Embryo, Mammalian
- Gene Targeting
- Genetic Variation
- Isoenzymes
- Microscopy, Confocal
- Myosin Heavy Chains
- Myosins
- Neuromuscular Junction
- Nuclease Protection Assays
- Oculomotor Muscles
- Orbit
- RNA, Messenger
- Rats
- Ribonucleases
- Tissue Distribution
