Article
Visual system maldevelopment disrupts extraocular muscle-specific myosin expression.
Journal of applied physiology (Bethesda, Md. : 1985) - 1 Aug 1998
Brueckner J K, Porter J D
Abstract excerpt
The genetic and epigenetic influences that are responsible for the establishment and maintenance of the unique phenotype of the extraocular muscles (EOMs) are poorly understood. A role for visual cues in shaping EOM maturation was assessed in rats by using two visual deprivation paradigms, dark r...
Topics
- Animals
- Blotting, Northern
- Darkness
- Immunohistochemistry
- In Situ Hybridization
- Isoenzymes
- Myosin Heavy Chains
- Myosins
- Oculomotor Muscles
- Oligonucleotide Probes
- Phenotype
- RNA, Messenger
- Rats
- Vision, Monocular
- Vision, Ocular
