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Article

Regulation of Egr-1, SRF, and Sp1 mRNA expression in contracting skeletal muscle cells.

Journal of applied physiology (Bethesda, Md. : 1985) - 1 Dec 2004

Irrcher Isabella, Hood David A

Abstract excerpt

The early cellular signals associated with contractile activity initiate the activation and induction of transcription factors that regulate changes in skeletal muscle phenotype. The transcription factors Egr-1, Sp1, and serum response factor (SRF) are potentially important mediators of mitochondrial biogenesis based on the prevalence of binding sites for them in the promoter regions of genes encoding...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 15310743
DOI: 10.1152/japplphysiol.00388.2004

Genes

SRF
PGC

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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