Article
Molecular analysis of WFDC1/ps20 gene in prostate cancer.
The Prostate - 1 Oct 2004
Watson J E Vivienne, Kamkar Shervin, James Karen, Kowbel David, Andaya Armann, Paris Pamela L, Simko Jeffry, Carroll Peter, McAlhany Stephanie, Rowley David, Collins Colin
Abstract excerpt
BACKGROUND: WFDC1/ps20 protein has been previously established as a growth suppressor of the prostate cancer cell line PC3. It maps to chromosome 16q23.1, a region of frequent loss of heterozygosity, familial association, and genomic loss in prostate cancer. We, therefore, chose to examine WFDC1/ps20 for mutations and expression changes in prostate cancer. METHODS: DNA from 21 prostate cancer patients and 5...
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