Article
Esophageal muscle physiology and morphogenesis require assembly of a collagen XIX-rich basement membrane zone.
The Journal of cell biology - 16 Aug 2004
Sumiyoshi Hideaki, Mor Niv, Lee Sui Y, Doty Stephen, Henderson Scott, Tanaka Shizuko, Yoshioka Hidekatsu, Rattan Satish, Ramirez Francesco
Abstract excerpt
Collagen XIX is an extremely rare extracellular matrix component that localizes to basement membrane zones and is transiently expressed by differentiating muscle cells. Characterization of mice harboring null and structural mutations of the collagen XIX (Col19a1) gene has revealed the critical contribution of this matrix protein to muscle physiology and differentiation. The phenotype includes smooth muscle motor...
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