Mouse Col18a1 is expressed in a tissue-specific manner as three alternative variants and is localized in basement membrane zones.

doi:10.1073/pnas.92.19.8763

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Back to search

Article

Mouse Col18a1 is expressed in a tissue-specific manner as three alternative variants and is localized in basement membrane zones.

Proceedings of the National Academy of Sciences of the United States of America - 12 Sept 1995

Muragaki Y, Timmons S, Griffith C M, Oh S P, Fadel B, Quertermous T, Olsen B R

Abstract excerpt

We have isolated overlapping cDNAs encoding the N-terminal non-triple-helical region of mouse alpha 1(XVIII) collagen and shown that three different variants of alpha 1(XVIII) collagen exist. Each of the three variants shows characteristic tissue-specific expression patterns. Immunohistochemical studies show positive staining for alpha 1(XVIII) collagen along the basement membrane zones of vessels in the...

Topics

Alternative Splicing
Amino Acid Sequence
Animals
Base Sequence
Basement Membrane
Blood Vessels
Blotting, Northern
Cloning, Molecular
Collagen
DNA, Complementary

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Embryo, Mammalian

Genetic Variation

Immunohistochemistry

Mice

Molecular Sequence Data

Protein Structure, Secondary

Tissue Distribution

Source

Open in PubMed Open full text

Identifiers

PMID: 7568013
DOI: 10.1073/pnas.92.19.8763
PMCID: PMC41047

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-7568013-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

discussions

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Mouse Col18a1 is expressed in a tissue-specific manner as three alternative variants and is localized in basement membrane zones.PMID 7568013Read ↗

Isolation and sequencing of cDNAs for proteins with multiple domains of Gly-Xaa-Yaa repeats identify a distinct family of collagenous proteins.Semantic proximity Read ↗

Collagen XV, a multifaceted multiplexin present across tissues and speciesSemantic proximity Read ↗

Type XV collagen exhibits a widespread distribution in human tissues but a distinct localization in basement membrane zonesSemantic proximity Read ↗

Type III collagen affects dermal and vascular collagen fibrillogenesis and tissue integrity in a mutant Col3a1 transgenic mouse model.Semantic proximity Read ↗

Collagen XVIII in tissue homeostasis and dysregulation — Lessons learned from model organisms and human patientsSemantic proximity Read ↗

Mammalian collagen IVSemantic proximity Read ↗

Transmembrane collagen XVII is a novel component of the glomerular filtration barrier.Semantic proximity Read ↗

Collagen XVII.Semantic proximity Read ↗

Primary structure of the long and short splice variants of mouse collagen XII and their tissue‐specific expression during embryonic developmentSemantic proximity Read ↗

Structurally altered basement membranes and hydrocephalus in a type XVIII collagen deficient mouse lineSemantic proximity Read ↗

Type IV collagen drives alveolar epithelial-endothelial association and the morphogenetic movements of septation.Semantic proximity Read ↗

The human alpha 1(XV) collagen chain contains a large amino-terminal non-triple helical domain with a tandem repeat structure and homology to alpha 1(XVIII) collagen.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.