Article
F exclusion of bacteriophage T7 occurs at the cell membrane.
Virology - 1 Sept 2004
Cheng Xiaogang, Wang WenFang, Molineux Ian J
Abstract excerpt
The F plasmid PifA protein, known to be the cause of F exclusion of bacteriophage T7, is shown to be a membrane-associated protein. No transmembrane domains of PifA were located. In contrast, T7 gp1.2 and gp10, the two phage proteins that trigger phage exclusion, are both soluble cytoplasmic proteins. The Escherichia coli FxsA protein, which, at higher concentrations than found in wild-type cells, protects T7...
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