Article
Identification and characterization of viral antagonists of type I interferon in negative-strand RNA viruses.
Current topics in microbiology and immunology - 1 Jan 2004
García-Sastre A
Abstract excerpt
Interferons are cytokines secreted in response to viral infections with potent antiviral activity, and they represent a critical component of the innate immune response against viruses. It has now become apparent that many viruses have evolved different mechanisms to counteract the interferon response, allowing their efficient replication and propagation in their hosts. This review discusses how the development...
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