Article
Complex cis-elements determine an RNA editing site in pea mitochondria.
Nucleic acids research - 1 Jan 2004
Takenaka Mizuki, Neuwirt Julia, Brennicke Axel
Abstract excerpt
The cis-requirements for the first editing site in the atp9 mRNA from pea mitochondria were investigated in an in vitro RNA editing system. Template RNAs deleted 5' of -20 are edited correctly, but with decreased efficiency. Deletions between -20 and the edited nucleotide abolish editing activity. Substitution of the sequences 3' of the editing site has little effect, which suggests that the major determinants...
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