Article
The IL-6 gene G-174C polymorphism related to health indices in Greek primary school children.
Obesity research - 1 Jul 2004
Dedoussis George V Z, Manios Yannis, Choumerianou Despoina M, Yiannakouris Nikos, Panagiotakos Demosthenes B, Skenderi Katerina, Zampelas Antonis
Abstract excerpt
Interleukin-6 (IL-6) is a pleiotropic cytokine expressed in many tissues. A polymorphism in the IL-6 gene, associated with differences in IL-6 transcription rate, has been recently described. Subjects with the -174GG genotype are prone to lipid abnormalities. We investigated the effect of the G-174C IL-6 polymorphism on health indices and lipid values of 184 Greek primary school children. The genotype...
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