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Article

Functional characterization of the yeast Ppz1 phosphatase inhibitory subunit Hal3: a mutagenesis study.

The Journal of biological chemistry - 8 Oct 2004

Muñoz Iván, Ruiz Amparo, Marquina Maribel, Barceló Anna, Albert Armando, Ariño Joaquín

Abstract excerpt

Saccharomyces cerevisiae Hal3 is a conserved protein that binds the carboxyl-terminal catalytic domain of the PP1c (protein phosphatase 1)-related phosphatase Ppz1 and potently inhibits its activity, thus modulating all of the characterized functions so far of the phosphatase. It is unknown how Hal3 binds to Ppz1 and inhibits its activity. Although it contains a putative protein phosphatase 1c binding-like...

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PMID: 15292171
DOI: 10.1074/jbc.M405656200

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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