Article
Identification and transcriptional organization of a gene cluster involved in biosynthesis and transport of acinetobactin, a siderophore produced by Acinetobacter baumannii ATCC 19606T.
Microbiology (Reading, England) - 1 Aug 2004
Mihara Kazutoshi, Tanabe Tomotaka, Yamakawa Yoshiko, Funahashi Tatsuya, Nakao Hiroshi, Narimatsu Shizuo, Yamamoto Shigeo
Abstract excerpt
In order to assimilate iron, Acinetobacter baumannii ATCC 19606(T) produces a siderophore named acinetobactin (Ab) that is composed of equimolar quantities of 2,3-dihydroxybenzoic acid (DHBA), L-threonine and N-hydroxyhistamine. Application of the Fur titration assay system to A. baumannii genomic libraries, followed by further cloning of the regions surrounding the candidate genes, led to the identification of...
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