Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Identification and cloning of the gene involved in the final step of chlortetracycline biosynthesis in Streptomyces aureofaciens.

Bioscience, biotechnology, and biochemistry - 1 Jun 2004

Nakano Tetsuo, Miyake Koichiro, Endo Hirofumi, Dairi Tohru, Mizukami Toru, Katsumata Ryoichi

Abstract excerpt

For chlortetracycline biosynthesis in Streptomyces aureofaciens, the final reduction step is essential to give an antibiotic activity to its intermediate, which is catalyzed by tetracycline dehydrogenase with 7,8-dedimethyl-8-hydroxy-5-deazariboflavin (FO) as a cofactor. We identified and cloned...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Base Sequence
Share to Cloning, Molecular
Share to Molecular Sequence Data

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Multigene Family

Share to Mutation

Share to Open Reading Frames

Share to Oxidoreductases

Source

Identifiers

PMID: 15215601
DOI: 10.1271/bbb.68.1345

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026. Prepared record publication-15215601-2026-09-01.1. Manifest publication-graph-cohort-2026-09-01.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 1 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Identification and cloning of the gene involved in the final step of chlortetracycline biosynthesis in Streptomyces aureofaciens.PMID 15215601Read ↗

Deciphering and engineering of the final step halogenase for improved chlortetracycline biosynthesis in industrial Streptomyces aureofaciensSemantic proximity Read ↗

Identification and transcriptional organization of a gene cluster involved in biosynthesis and transport of acinetobactin, a siderophore produced by Acinetobacter baumannii ATCC 19606T.Semantic proximity Read ↗

Gene cluster involved in the biosynthesis of griseobactin, a catechol-peptide siderophore of Streptomyces sp. ATCC 700974.Semantic proximity Read ↗

Biosynthesis of Oxytetracycline by Streptomyces rimosus: Past, Present and Future Directions in the Development of Tetracycline AntibioticsSemantic proximity Read ↗

Genes Involved in the Biosynthesis and Transport of Acinetobactin in<i>Acinetobacter baumannii</i>Semantic proximity Read ↗

Organisation and functions of the actVA region of the actinorhodin biosynthetic gene cluster of Streptomyces coelicolor.Semantic proximity Read ↗

Mechanism of the incidental production of a melanin-like pigment during 6-demethylchlortetracycline production in Streptomyces aureofaciens.Semantic proximity Read ↗

Cloning and mapping of the dihydrofolate reductase gene of Bacillus subtilis.Semantic proximity Read ↗

Identification of a monooxygenase from Streptomyces coelicolor A3(2) involved in biosynthesis of actinorhodin: purification and characterization of the recombinant enzyme.Semantic proximity Read ↗

Transcriptional organization of ThnI-regulated thienamycin biosynthetic genes in Streptomyces cattleya.Semantic proximity Read ↗

The biosynthetic gene cluster for the beta-lactam carbapenem thienamycin in Streptomyces cattleya.Semantic proximity Read ↗

Occurrence of a putative ancient-like isomerase involved in histidine and tryptophan biosynthesis.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.