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Article

Involvement of Leishmania donovani major surface glycoprotein gp63 in promastigote multiplication.

Journal of biosciences - 1 Mar 2004

Pandey Sanjeev, Chakraborti Phuljhuri, Sharma Rakhi, Bandyopadhyay Santu, Sarkar Dwijen, Adhya Samit

Abstract excerpt

The major surface glycoprotein gp63 of the kinetoplastid protozoal parasite Leishmania is implicated as a ligand mediating uptake of the parasite into, and survival within, the host macrophage. By expressing gp63 antisense RNA from an episomal vector in L. donovani promastigotes, gp63-deficient transfectants were obtained. Reduction of the gp63 level resulted in increased generation times, altered cell...

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PMID: 15286399
DOI: 10.1007/BF02702557

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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