Article
Sequence diversity and organization of the msp gene family encoding gp63 of Leishmania chagasi.
Molecular and biochemical parasitology - 1 Dec 1993
Roberts S C, Swihart K G, Agey M W, Ramamoorthy R, Wilson M E, Donelson J E
Abstract excerpt
During in vitro growth Leishmania chagasi promastigotes differentially express 3 classes of RNAs encoding the major surface protease (MSP) gp63 that can be distinguished by their unique 3' untranslated regions. Here we show that the three classes (logarithmic-specific, stationary-specific and constitutively expressed) are encoded by a family of at least 4 tandem stationary genes (mspS2, mspS1, mspS3 and mspS5)...
Topics
- Amino Acid Sequence
- Animals
- Base Sequence
- Cricetinae
- DNA, Protozoan
- Genes, Protozoan
- Genetic Variation
- Introns
- Leishmania
- Leishmaniasis
- Mesocricetus