Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The presence of hereditary BRCA1 gene mutations in women with familial breast or ovarian cancer and the frequency of occurrence of these tumours in their relatives.

European journal of gynaecological oncology - 1 Jan 2004

Skasko E, Paszko Z, Niwińska A, Kwiatkowska E, Kruczek A, Pieńkowski T

Abstract excerpt

UNLABELLED: In 48 women with familial breast cancer as well as in 22 women with familial ovarian cancer, the presence of pathogenic mutations in BRCA1 gene were found in 35.4% and 54.6% of patients, respectively. From the patients with mutations we created two groups: the CaM--probands with breast cancer and CaOv--probands with ovarian cancer. The probands with breast cancer were younger by a mean of five years...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Age Factors
Share to Breast Neoplasms

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Genes, BRCA1

Share to Incidence

Share to Ovarian Neoplasms

Share to Poland

Share to Reverse Transcriptase Polymerase Chain Reaction

Share to Sensitivity and Specificity

Source

Identifiers

PMID: 15285306

Genes

BRCA1

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The presence of hereditary BRCA1 gene mutations in women with familial breast or ovarian cancer and the frequency of occurrence of these tumours in their relatives.PMID 15285306Read ↗

Cancer risks in first degree relatives of BRCA1 mutation carriers: effects of mutation and proband disease status.Semantic proximity Read ↗

Hereditary Breast-Ovarian Cancer and BRCA1 / BRCA2 variants: a single center experienceSemantic proximity Read ↗

Prevalence of BRCA1 mutations in familial and sporadic greek ovarian cancer cases.Semantic proximity Read ↗

BRCA1 germline mutations and polymorphisms in a clinic-based series of ovarian cancer cases: a Gynecologic Oncology Group study.Semantic proximity Read ↗

A high proportion of mutations in the BRCA1 gene in German breast/ovarian cancer families with clustering of mutations in the 3' third of the gene.Semantic proximity Read ↗

Germline mutations of the BRCA1 gene in breast and ovarian cancer families provide evidence for a genotype-phenotype correlation.Semantic proximity Read ↗

One in 10 ovarian cancer patients carry germ line BRCA1 or BRCA2 mutations: results of a prospective study in Southern Sweden.Semantic proximity Read ↗

Limited significance of family history for presence of BRCA1 gene mutation in Polish breast and ovarian cancer cases.Semantic proximity Read ↗

Incidence of BRCA1 and BRCA2 mutations in 54 Chilean families with breast/ovarian cancer, genotype-phenotype correlations.Semantic proximity Read ↗

BRCA1 mutations and polymorphisms in a hospital-based consecutive series of breast cancer patients from Apulia, Italy.Semantic proximity Read ↗

Contribution of BRCA1 and BRCA2 to familial ovarian cancer: a gynecologic oncology group study.Semantic proximity Read ↗

Novel germline BRCA1 and BRCA2 mutations in Turkish women with breast and/or ovarian cancer and their relatives.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.