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<i>In vivo</i> and <i>in vitro</i> differentiation of male germ cells in the mouse

27 Jul 2004

Abstract excerpt

Primordial germ cells appear in the embryo at about day 7 after coitum. They proliferate and migrate towards the genital ridge. Once there, they undergo differentiation into germ stem cells, known as 'A spermatogonia'. These cells are the foundation of spermatogenesis. A spermatogonia commit to spermatogenesis, stay undifferentiated or degenerate. The differentiation of primordial germ cells to migratory,...

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PMID: 15280553
DOI: 10.1530/rep.1.00220

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