Article
A common antitussive drug, clobutinol, precipitates the long QT syndrome 2.
Molecular pharmacology - 1 Nov 2004
Bellocq Chloé, Wilders Ronald, Schott Jean-Jacques, Louérat-Oriou Bénédicte, Boisseau Pierre, Le Marec Hervé, Escande Denis, Baró Isabelle
Abstract excerpt
QT prolongation, a classic risk factor for arrhythmias, can result from a mutation in one of the genes governing cardiac repolarization and also can result from the intake of a medication acting as blocker of the cardiac K(+) channel human ether-a-go-go-related gene (HERG). Here, we identified th...
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