Article
Predominant clonal evolution leads to a close parity between gene expression profiles and subspecific phylogeny in Trypanosoma cruzi.
Molecular and biochemical parasitology - 1 Sept 2004
Telleria Jenny, Barnabé Christian, Hide Mallorie, Bañuls Anne-Laure, Tibayrenc Michel
Abstract excerpt
We investigated the relationships between overall phylogenetic diversity in Trypanosoma cruzi evidenced by multilocus markers (MLEE and RAPD) on the one hand, and gene expression patterns, revealed by mRNA analysis on the other hand. Nineteen laboratory-cloned stocks representative of this parasite's overall phylogenetic diversity and ecogeographical range were analyzed using random amplified differentially...
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