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Transcriptional and phenotypical heterogeneity of <i>Trypanosoma cruzi</i> cell populations

1 Dec 2015

Abstract excerpt

Trypanosoma cruzi has a complex life cycle comprising pools of cell populations which circulate among humans, vectors, sylvatic reservoirs and domestic animals. Recent experimental evidence has demonstrated the importance of clonal variations for parasite population dynamics, survival and evolution. By limiting dilution assays, we have isolated seven isogenic clonal cell lines derived from the Pan4 strain of T....

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PMID: 26674416
DOI: 10.1098/rsob.150190

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