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Article

Trypanosoma cruzi: gene expression surveyed by proteomic analysis reveals interaction between different genotypes in mixed in vitro cultures.

PloS one - 1 Jan 2014

Machin Alexandre, Telleria Jenny, Brizard Jean-Paul, Demettre Edith, Séveno Martial, Ayala Francisco José, Tibayrenc Michel

Abstract excerpt

We have analyzed the comportment in in vitro culture of 2 different genotypes of Trypanosoma cruzi, the agent of Chagas disease, pertaining to 2 major genetic subdivisions (near-clades) of this parasite. One of the stocks was a fast-growing one, highly virulent in mice, while the other one was slow-growing, mildly virulent in mice. The working hypothesis was that mixtures of genotypes interact, a pattern that has...

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Identifiers

PMID: 24748035
DOI: 10.1371/journal.pone.0095442
PMCID: PMC3991653

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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