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Article

UDP-glucose pyrophosphorylase is upregulated in carriers of the porcine RN- mutation in the AMP-activated protein kinase.

Proteomics - 1 Aug 2004

Hedegaard Jakob, Horn Per, Lametsch René, Søndergaard Møller Hanne, Roepstorff Peter, Bendixen Christian, Bendixen Emøke

Abstract excerpt

The AMP-activated protein kinase (AMPK) plays a key role in the regulation of energy metabolism in eukaryotic cells acting as a metabolic sensor. In its activated form AMPK inhibits ATP consuming pathways and stimulates ATP generating pathways. A dominant mutation, denoted RN(-), in the porcine PRKAG3 gene, encoding the regulatory gamma3 subunit of AMPK, results in hyperaccumulation of glycogen in glycolytic...

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Identifiers

PMID: 15274139
DOI: 10.1002/pmic.200300761

Genes

PRKAG3

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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