Article
Molecular characterization and mutational screening of the PRKAG3 gene in the horse.
Cytogenetic and genome research - 1 Jan 2003
Park H B, Marklund S, Jeon J T, Mickelson J R, Valberg S J, Sandberg K, Andersson L
Abstract excerpt
The PRKAG3 gene encodes a muscle-specific isoform of the regulatory gamma subunit of AMP-activated protein kinase (AMPK). A major part of the coding PRKAG3 sequence was isolated from horse muscle cDNA using reverse-transcriptase (RT)-PCR analysis. Horse-specific primers were used to amplify genomic fragments containing 12 exons. Comparative sequence analysis of horse, pig, mouse, human, Fugu, and zebrafish was...
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