Article
Alternative mutations of BRAF, RET and NTRK1 are associated with similar but distinct gene expression patterns in papillary thyroid cancer.
Oncogene - 23 Sept 2004
Frattini Milo, Ferrario Cristina, Bressan Paola, Balestra Debora, De Cecco Loris, Mondellini Piera, Bongarzone Italia, Collini Paola, Gariboldi Manuela, Pilotti Silvana, Pierotti Marco A, Greco Angela
Abstract excerpt
Papillary thyroid carcinoma (PTC) is associated with RET and NTRK1 rearrangements and BRAF mutations. A series of 60 PTCs collected in a single center from Italian patients were histologically re-examined and subclassified as well differentiated or tall cell variant. The sample collection was analysed for the presence of all the reported PTC-associated genetic alterations through DNA or cDNA amplification,...
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