Long-term survivors in Nairobi: complete HIV-1 RNA sequences and immunogenetic associations.

doi:10.1086/421504

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Article

Long-term survivors in Nairobi: complete HIV-1 RNA sequences and immunogenetic associations.

The Journal of infectious diseases - 15 Aug 2004

Fang Guowei, Kuiken Carla, Weiser Barbara, Rowland-Jones Sarah, Plummer Francis, Chen Chih-Hsiung, Kaul Rupert, Anzala Aggrey Omu, Bwayo Job, Kimani Joshua, Philpott Sean M, Kitchen Christina, Sinsheimer Janet S, Gaschen Brian, Lang Dorothy, Shi Binshan, Kemal Kimdar Sherefa, Rostron Tim, Brunner Cheryl, Beddows Simon, Sattenau Quentin, Paxinos Ellen, Oyugi Julius, Burger Harold

Abstract excerpt

To investigate African long-term survivors (LTSs) infected with non-subtype B human immunodeficiency virus type 1 (HIV-1), we obtained full-length HIV-1 RNA sequences and immunogenetic profiles from 6 untreated women enrolled in the Pumwani Sex Worker Cohort in Nairobi, Kenya. There were no discernible sequence changes likely to cause attenuation. CCR2-V64I, an immunogenetic polymorphism linked to LTSs, was...

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PMID: 15272396
DOI: 10.1086/421504

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